• A Novel Method of Fetal Cardioversion

      Sanghavi, Darshak M. (2012-04-15)
      The ideal treatment for fetal arrhythmias associated with hydrops is not known. This case report describes a novel approach to fetal cardioversion using oral maternal bolus dosing of flecainide.
    • Speckle echocardiographic left atrial strain and stiffness index as predictors of maintenance of sinus rhythm after cardioversion for atrial fibrillation: a prospective study

      Shaikh, Amir Y.; Mann, Abhishek; Khan, Umar A.; Aurigemma, Gerard P.; Hill, Jeffrey C.; Kane, Jennifer L.; Tighe, Dennis A.; Mick, Eric; McManus, David D. (2012-12-03)
      BACKGROUND: Echocardiographic left atrial (LA) strain parameters have been associated with atrial fibrillation (AF) in prior studies. Our goal was to determine if strain measures [peak systolic longitudinal strain (LAS) and stiffness index (LASt)] changed after cardioversion (CV); and their relation to AF recurrence. METHODS AND RESULTS: 46 participants with persistent AF and 41 age-matched participants with no AF were recruited. LAS and LASt were measured before and immediately after CV using 2D speckle tracking imaging (2DSI). Maintenance of sinus rhythm was assessed over a 6-month follow up. Mean LAS was lower, and mean LASt higher, in participants with AF before CV as compared to control group (11.9 +/- 1.0 vs 35.7 +/- 1.7, p CONCLUSIONS: LAS and LASt differed between participants with and without AF, irrespective of the rhythm at the time of echocardiographic assessment. Baseline LAS and LASt were not associated with AF recurrence. However, change in LAS after CV may be a useful predictor of recurrent arrhythmia.