Browsing by keyword "sitting time"
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Change in Physical Activity and Sitting Time After Myocardial Infarction and Mortality Among Postmenopausal Women in the Women's Health Initiative-Observational StudyBACKGROUND: How physical activity (PA) and sitting time may change after first myocardial infarction (MI) and the association with mortality in postmenopausal women is unknown. METHODS AND RESULTS: Participants included postmenopausal women in the Women's Health Initiative-Observational Study, aged 50 to 79 years who experienced a clinical MI during the study. This analysis included 856 women who had adequate data on PA exposure and 533 women for sitting time exposures. Sitting time was self-reported at baseline, year 3, and year 6. Self-reported PA was reported at baseline through year 8. Change in PA and sitting time were calculated as the difference between the cumulative average immediately following MI and the cumulative average immediately preceding MI. The 4 categories of change were: maintained low, decreased, increased, and maintained high. The cut points were > /=7.5 metabolic equivalent of task hours/week versus /=8 h/day versus /day for sitting time. Cox proportional hazard models estimated hazard ratios and 95% CIs for all-cause, coronary heart disease, and cardiovascular disease mortality. Compared with women who maintained low PA (referent), the risk of all-cause mortality was: 0.54 (0.34-0.86) for increased PA and 0.52 (0.36-0.73) for maintained high PA. Women who had pre-MI levels of sitting time /day, every 1 h/day increase in sitting time was associated with a 9% increased risk (hazard ratio=1.09, 95% CI: 1.01, 1.19) of all-cause mortality. CONCLUSIONS: Meeting the recommended PA guidelines pre- and post-MI may have a protective role against mortality in postmenopausal women.
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The influence of physical activity and sedentary behavior on living to age 85 years without disease and disability in older womenBackground: Whether physical activity (PA) and sedentary behavior influence the odds of women living to age 85 years without chronic disease or disability is not well described. Methods: Participants of the Women's Health Initiative (n=49,612) were categorized based on health status by age 85 years: 1) lived without developing major chronic disease or mobility disability ("healthy"); 2) lived and developed mobility disability with or without disease; 3) lived and developed major chronic disease, but not mobility disability; and 4) died before their 85 th birth year. Multinomial logistic regression models that adjusted for covariates such as age, race/ethnicity, and body size estimated associations of self-reported PA and sitting time on developing major disease or mobility disability or dying before age 85 relative to being healthy. Results: Mean+/-SD baseline age was 70.2+/-3.6 years. Distributions were: 22% healthy, 23% had mobility disability, 26% had major disease, 29% died. Relative to those with high total PA, the adjusted OR (CI) for mobility disability was 1.6 (1.4-1.7), 1.2 (1.1-1.3), and 1.1 (1.0-1.2) for women with no, low, and moderate total PA, respectively (p-trend < 0.001). The corresponding covariate-adjusted OR (CI) for mortality was 1.7 (1.5-1.8), 1.2 (1.1-1.3), and 1.0 (1.0-1.1) (p-trend < 0.001). Total PA was not associated with developing chronic disease before age 85 years. Sitting > /=10 relative to < 5 hours/day increased the odds of mobility disability (1.1, CI: 1.0-1.3) and mortality (1.2, CI: 1.0-1.3) prior to age 85 years (p < 0.001). Conclusions: Increasing PA to recommended levels and reducing sitting time are modifiable behaviors that may improve healthy aging in older women.
