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    Date Issued2012 (1)AuthorKaufman, Paul D. (1)
    Lopes da Rosa, Jessica (1)
    UMass Chan AffiliationProgram in Gene Function and Expression (1)Document TypeJournal Article (1)KeywordBiochemistry (1)Candida albicans (1)Candidiasis (1)Chromatin (1)Chromatin modification (1)View MoreJournalBiochimica et biophysica acta (1)

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    Chromatin-mediated Candida albicans virulence

    Lopes da Rosa, Jessica; Kaufman, Paul D. (2012-01-01)
    Candida albicans is the most prevalent human fungal pathogen. To successfully propagate an infection, this organism relies on the ability to change morphology, express virulence-associated genes and resist DNA damage caused by the host immune system. Many of these events involve chromatin alterations that are crucial for virulence. This review will focus on the studies that have been conducted on how chromatin function affects pathogenicity of C. albicans and other fungi. This article is part of a Special Issue entitled: Histone chaperones and Chromatin assembly.
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