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Correlates of suicidality among patients with psychotic depression
The independent association of age and other factors with suicidality in patients with major depression with psychotic features was examined. Of the 183 study participants, 21% had a suicide attempt during the current episode. Male gender, Hispanic background, past suicide attempt, higher depression scores, and higher cognitive scores were each independently associated with greater intensity of current suicidality. Older age was independently associated with a lower risk of a lifetime suicide attempt. These findings reinforce the evidence that patients with psychotic depression are at high risk for suicide and underscore the importance of examining correlates of suicidality specific to patients with psychotic depression.
Research Assessment of Patients With Psychotic Depression: The STOP-PD Approach
Major depression with psychotic features (psychotic depression) is a severe, disabling disorder. Compared with nonpsychotic major depression, psychotic depression has been associated with greater severity of depressive symptoms, greater functional impairment, increased risk of suicide, lower rate of recovery, increased risk of depressive relapse and recurrence, and more frequent hospital admissions. There are significant challenges in conducting a treatment study of psychotic depression, including the recruitment, retention, and assessment of patients.