Serologic Screening for Genital Herpes Infection: US Preventive Services Task Force Reaffirmation Recommendation Statement

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dc.contributor.authorMangione, Carol M
dc.contributor.authorBarry, Michael J
dc.contributor.authorNicholson, Wanda K
dc.contributor.authorCabana, Michael
dc.contributor.authorChelmow, David
dc.contributor.authorCoker, Tumaini Rucker
dc.contributor.authorDavis, Esa M
dc.contributor.authorDonahue, Katrina E
dc.contributor.authorJaén, Carlos Roberto
dc.contributor.authorKubik, Martha
dc.contributor.authorLi, Li
dc.contributor.authorOgedegbe, Gbenga
dc.contributor.authorPbert, Lori
dc.contributor.authorRuiz, John M
dc.contributor.authorStevermer, James
dc.contributor.authorWong, John B
dc.contributor.departmentPopulation and Quantitative Health Sciencesen_US
dc.contributor.departmentPrevention Research Centeren_US
dc.date.accessioned2023-03-17T17:47:55Z
dc.date.available2023-03-17T17:47:55Z
dc.date.issued2023-02-14
dc.description.abstractImportance: Genital herpes is a common sexually transmitted infection caused by 2 related viruses, herpes simplex type 1 (HSV-1) and herpes simplex type 2 (HSV-2). Infection is lifelong; currently, there is no cure for HSV infection. Antiviral medications may provide clinical benefits to symptomatic persons. Transmission of HSV from a pregnant person to their infant can occur, most commonly during delivery; when genital lesions or prodromal symptoms are present, cesarean delivery can reduce the risk of transmission. Neonatal herpes infection is uncommon yet can result in substantial morbidity and mortality. Objective: To reaffirm its 2016 recommendation, the US Preventive Services Task Force (USPSTF) commissioned a reaffirmation evidence update on targeted key questions to systematically evaluate the evidence on accuracy, benefits, and harms of routine serologic screening for HSV-2 infection in asymptomatic adolescents, adults, and pregnant persons. Population: Adolescents and adults, including pregnant persons, without known history, signs, or symptoms of genital HSV infection. Evidence assessment: The USPSTF concludes with moderate certainty that the harms outweigh the benefits for population-based screening for genital HSV infection in asymptomatic adolescents and adults, including pregnant persons. Recommendation: The USPSTF recommends against routine serologic screening for genital HSV infection in asymptomatic adolescents and adults, including pregnant persons. (D recommendation).en_US
dc.identifier.citationUS Preventive Services Task Force; Mangione CM, Barry MJ, Nicholson WK, Cabana M, Chelmow D, Coker TR, Davis EM, Donahue KE, Jaén CR, Kubik M, Li L, Ogedegbe G, Pbert L, Ruiz JM, Stevermer J, Wong JB. Serologic Screening for Genital Herpes Infection: US Preventive Services Task Force Reaffirmation Recommendation Statement. JAMA. 2023 Feb 14;329(6):502-507. doi: 10.1001/jama.2023.0057. PMID: 36786784.en_US
dc.identifier.doi10.1001/jama.2023.0057en_US
dc.identifier.eissn1538-3598
dc.identifier.journalJAMA
dc.identifier.pmid36786784
dc.identifier.urihttps://hdl.handle.net/20.500.14038/51844
dc.language.isoenen_US
dc.relation.ispartofJAMAen_US
dc.relation.urlhttps://doi.org/10.1001/jama.2023.0057en_US
dc.source.beginpage502
dc.source.countryUnited States
dc.source.endpage507
dc.source.issue6
dc.source.journaltitleJAMA
dc.source.volume329
dc.titleSerologic Screening for Genital Herpes Infection: US Preventive Services Task Force Reaffirmation Recommendation Statementen_US
dc.typeJournal Articleen_US
dspace.entity.typePublication
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