Loading...
Thumbnail Image
Publication

Simultaneous optogenetic manipulation and calcium imaging in freely moving C. elegans [preprint]

Shipley, Frederick B.
Clark, Christopher M.
Alkema, Mark J
Leifer, Andrew M.
Embargo Expiration Date
Link to Full Text
Abstract

A fundamental goal of systems neuroscience is to probe the dynamics of neural activity that drive behavior. Here we present an instrument to simultaneously manipulate neural activity via Channelrhodopsin, monitor neural response via GCaMP3, and observes behavior in freely moving C. elegans. We use the instrument to directly observe the relation between sensory stimuli, interneuron activity and locomotion in the mechanosensory circuit. Now published as: Front Neural Circuits 8:28, doi:10.3389/fncir.2014.00028

Source

bioRxiv 000943; doi: https://doi.org/10.1101/000943. Link to preprint on bioRxiv service.

Year of Medical School at Time of Visit
Sponsors
Dates of Travel
DOI
10.1101/000943
PubMed ID
Other Identifiers
Notes
Funding and Acknowledgements
Corresponding Author
Related Resources

Now published in Front Neural Circuits 8:28, doi:10.3389/fncir.2014.00028

Related Resources
Repository Citation
Rights
The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It is made available under a CC-BY-NC 4.0 International license.