An ongoing pilot study of PRISM (PRogram In Support of Moms) suggests that while both MCPAP (Massachusetts Child Psychiatry Access Project) for Moms and PRISM improve maternal perinatal depression symptoms, there is a greater decrease in depression severity with the additional intervention components included in PRISM. Over the next 5 years, investigators will run a randomized control trial that compares a set of 6 Massachusetts practices using MCPAP for Moms to a set of 6 practices using MCPAP for Moms plus PRISM. A Spanish translation of this publication is available for download.