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Cyclonite-Induced Seizures After Voluntary C-4 Ingestion

Fang, Ton
Karandikar, Paramesh V
Young, Taylor R
Umeton, Raffaella P
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UMass Chan Affiliations
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Case Reports
Publication Date
2023-10-26
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Abstract

Cyclonite (cyclotrimethylenetrinitramine, RDX, hexogen) is the active agent in the plastic explosive, composition 4 (C-4). It has been used globally since the Vietnam War for both military and civilian applications due to its metastable nature. Ingestion or inhalation of C-4 can cause euphoric effects such as those commonly seen with alcohol toxicity, in addition to seizures and rarely fulminant liver and kidney failure. We report the case of a patient who ingested 75 g of C-4 and presented with a generalized tonic-clonic seizure four hours after ingestion. Our patient made a full recovery after being stabilized with temporizing anticonvulsants in the intensive care unit.

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Fang T, Karandikar PV, Young TR, Umeton RP. Cyclonite-Induced Seizures After Voluntary C-4 Ingestion. Cureus. 2023 Oct 26;15(10):e47746. doi: 10.7759/cureus.47746. PMID: 38021663; PMCID: PMC10676266.

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DOI
10.7759/cureus.47746
PubMed ID
38021663
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© Copyright 2023 Fang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.