Toward a common standard for data and specimen provenance in life sciences
Wittner, Rudolf ; Holub, Petr ; Mascia, Cecilia ; Frexia, Francesca ; Müller, Heimo ; Plass, Markus ; Allocca, Clare ; Betsou, Fay ; Burdett, Tony ; Cancio, Ibon ... show 10 more
Citations
Authors
Holub, Petr
Mascia, Cecilia
Frexia, Francesca
Müller, Heimo
Plass, Markus
Allocca, Clare
Betsou, Fay
Burdett, Tony
Cancio, Ibon
Chapman, Adriane
Chapman, Martin
Courtot, Mélanie
Curcin, Vasa
Eder, Johann
Elliot, Mark
Exter, Katrina
Goble, Carole
Golebiewski, Martin
Kisler, Bron
Kremer, Andreas
Leo, Simone
Lin-Gibson, Sheng
Marsano, Anna
Mattavelli, Marco
Moore, Josh
Nakae, Hiroki
Perseil, Isabelle
Salman, Ayat
Sluka, James
Soiland-Reyes, Stian
Strambio-De-Castillia, Caterina
Sussman, Michael
Swedlow, Jason R
Zatloukal, Kurt
Geiger, Jörg
Student Authors
Faculty Advisor
Academic Program
UMass Chan Affiliations
Document Type
Publication Date
Subject Area
Embargo Expiration Date
Link to Full Text
Abstract
Open and practical exchange, dissemination, and reuse of specimens and data have become a fundamental requirement for life sciences research. The quality of the data obtained and thus the findings and knowledge derived is thus significantly influenced by the quality of the samples, the experimental methods, and the data analysis. Therefore, a comprehensive and precise documentation of the pre-analytical conditions, the analytical procedures, and the data processing are essential to be able to assess the validity of the research results. With the increasing importance of the exchange, reuse, and sharing of data and samples, procedures are required that enable cross-organizational documentation, traceability, and non-repudiation. At present, this information on the provenance of samples and data is mostly either sparse, incomplete, or incoherent. Since there is no uniform framework, this information is usually only provided within the organization and not interoperably. At the same time, the collection and sharing of biological and environmental specimens increasingly require definition and documentation of benefit sharing and compliance to regulatory requirements rather than consideration of pure scientific needs. In this publication, we present an ongoing standardization effort to provide trustworthy machine-actionable documentation of the data lineage and specimens. We would like to invite experts from the biotechnology and biomedical fields to further contribute to the standard.
Source
Wittner R, Holub P, Mascia C, Frexia F, Müller H, Plass M, Allocca C, Betsou F, Burdett T, Cancio I, Chapman A, Chapman M, Courtot M, Curcin V, Eder J, Elliot M, Exter K, Goble C, Golebiewski M, Kisler B, Kremer A, Leo S, Lin-Gibson S, Marsano A, Mattavelli M, Moore J, Nakae H, Perseil I, Salman A, Sluka J, Soiland-Reyes S, Strambio-De-Castillia C, Sussman M, Swedlow JR, Zatloukal K, Geiger J. Toward a common standard for data and specimen provenance in life sciences. Learn Health Syst. 2023 Apr 18;8(1):e10365. doi: 10.1002/lrh2.10365. PMID: 38249839; PMCID: PMC10797572.
Year of Medical School at Time of Visit
Sponsors
Dates of Travel
DOI
Permanent Link to this Item
PubMed ID
Other Identifiers
Notes
Funding and Acknowledgements
Corresponding Author
Related Resources
This article is based on a previously available preprint in Zenodo, https://doi.org/10.5281/zenodo.5093125.