Two-way traffic: centrosomes and the cell cycle
Sluder, Greenfield
Sluder, Greenfield
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Student Authors
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UMass Chan Affiliations
Document Type
Journal Article
Publication Date
2005-10-19
Subject Area
Collections
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Abstract
The well recognized activities of the mammalian centrosome--microtubule nucleation, duplication, and organization of the primary cilium--are under the control of the cell cycle. However, the centrosome is more than just a follower of the cell cycle; it can also be essential for the cell to transit G1 and enter S phase. How the centrosome influences G1 progression is a mystery.
Source
Nat Rev Mol Cell Biol. 2005 Sep;6(9):743-8. Link to article on publisher's site
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DOI
10.1038/nrm1712
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PubMed ID
16231423