Membrane cytoskeleton: PIP(2) pulls the strings
Nebl, Thomas Oh, Sang W. Luna, Elizabeth J.
Nebl, Thomas
Oh, Sang W.
Luna, Elizabeth J.
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UMass Chan Affiliations
Document Type
Journal Article
Publication Date
2000-05-10
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Abstract
A recent application of optical tweezers has shown that plasma membrane phosphatidylinositol 4,5-bisphosphate (PIP(2)) levels control adhesion of the membrane bilayer to the underlying cytoskeleton, by regulated direct binding of PIP(2) to cytoskeletal proteins and/or indirect effects on cytoskeleton structure.
Source
Curr Biol. 2000 May 4;10(9):R351-4.
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DOI
10.1016/S0960-9822(00)00465-6
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PubMed ID
10801429