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Osteopontin: a bridge between bone and the immune system
Gravallese, Ellen M.
Gravallese, Ellen M.
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UMass Chan Affiliations
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Response or Comment
Publication Date
2003-07-17
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Abstract
The molecular mechanisms underlying the putative role of osteopontin in the chronic inflammatory disease rheumatoid arthritis are unclear. A study in a murine model of arthritis now demonstrates that a specific antibody directed against the exposed osteopontin epitope SLAYGLR is capable of preventing inflammatory cell infiltration in arthritic joints.
Source
J Clin Invest. 2003 Jul;112(2):147-9. Link to article on publisher's site
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DOI
10.1172/JCI19190
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PubMed ID
12865402
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Notes
At the time of publication, Ellen Gravallese was not yet affiliated with the University of Massachusetts Medical School.
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<p>Publisher PDF posted as allowed by the publisher's author rights policy at http://static.the-jci.org/content_assets/admin/forms/jcicopyright.pdf.</p>