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Severe Hemolytic Anemia due to Vitamin B12 Deficiency in Six Months

Sadagopan, Narayanan
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UMass Chan Affiliations
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Case Report
Publication Date
2022-06-22
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Abstract

Gastric bypass is a common cause of vitamin B12 deficiency. It can lead to patients presenting with symptoms of anemia. The body has significant reserves of vitamin B12 and loses vitamin B12 slowly. The following case is of a patient who underwent a gastric bypass five years ago and whose hemoglobin (Hgb) dropped from 12.2 g/dL to 4.4 g/dL over six months due to questionable adherence to vitamin supplements. Further work-up showed hemolytic anemia and thrombocytopenia due to a very low vitamin B12 level of 47 pg/mL, with his blood counts improving with vitamin B12 supplementation. The case points to the importance of thinking about vitamin deficiency as a cause of hemolysis to avoid unnecessary procedures.

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Sadagopan N. Severe Hemolytic Anemia due to Vitamin B12 Deficiency in Six Months. Hematol Rep. 2022 Jun 22;14(3):210-212. doi: 10.3390/hematolrep14030028. PMID: 35893152; PMCID: PMC9326528.

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DOI
10.3390/hematolrep14030028
PubMed ID
35893152
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Copyright: © 2022 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).Attribution 4.0 International