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Methodological Issues in Designing a Randomized Controlled Trial for Psychotic Depression: The STOP-PD Study

Meyers, Barnett S.
Peasley-Miklus, Catherine
Flint, Alastair J.
Mulsant, Benoit H.
Rothschild, Anthony J.
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Abstract

The safety and efficacy of electroconvulsive therapy (ECT) has been documented for more than half a century, including among patients with major depressive disorder with psychotic features (MD-Psy) who have failed intensive antidepressant treatment. More recent studies from academic centers that use contemporary ECT standards have demonstrated response and remission rates exceeding 90% among patients with MD-Psy.

Source

Meyers BS, Peasley-Miklus C, Flint AJ, Mulsant BH, Rothschild AJ: Methodological Issues In Designing A Randomized Controlled Trial For Psychotic Depression: The STOP-PD Study. Psych Annals, 2006; 36:57-64.

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