Stent-assisted Woven EndoBridge device for the treatment of intracranial aneurysms: an international multicenter study
Diestro, Jose Danilo Bengzon ; Dibas, Mahmoud ; Adeeb, Nimer ; Regenhardt, Robert W ; Vranic, Justin E ; Guenego, Adrien ; Lay, Sovann V ; Renieri, Leonardo ; Balushi, Ali Al ; Shotar, Eimad ... show 10 more
Citations
Authors
Dibas, Mahmoud
Adeeb, Nimer
Regenhardt, Robert W
Vranic, Justin E
Guenego, Adrien
Lay, Sovann V
Renieri, Leonardo
Balushi, Ali Al
Shotar, Eimad
Premat, Kévin
Namaani, Kareem El
Saliou, Guillaume
Möhlenbruch, Markus A
Lylyk, Ivan
Foreman, Paul M
Vachhani, Jay A
Župančić, Vedran
Hafeez, Muhammad U
Rutledge, Caleb
Rai, Hamid
Tutino, Vincent M
Mirshahi, Shervin
Ghozy, Sherief
Harker, Pablo
Alotaibi, Naif M
Rabinov, James D
Ren, Yifan
Schirmer, Clemens M
Goren, Oded
Piano, Mariangela
Kühn, Anna L
Michelozzi, Caterina
Elens, Stéphanie
Starke, Robert M
Hassan, Ameer E
Salehani, Arsalaan
Nguyen, Anh
Jones, Jesse
Psychogios, Marios
Spears, Julian
Marotta, Thomas
Pereira, Vitor
Parra-Fariñas, Carmen
Bres-Bullrich, Maria
Mayich, Michael
Salem, Mohamed M
Burkhardt, Jan-Karl
Jankowitz, Brian T
Domingo, Ricardo A
Huynh, Thien
Tawk, Rabih
Ulfert, Christian
Lubicz, Boris
Panni, Pietro
Puri, Ajit S
Pero, Guglielmo
Griessenauer, Christoph J
Asadi, Hamed
Siddiqui, Adnan
Ducruet, Andrew F
Albuquerque, Felipe C
Patel, Nirav
Kan, Peter
Kalousek, Vladimir
Lylyk, Pedro
Boddu, Srikanth
Stapleton, Christopher J
Knopman, Jared
Jabbour, Pascal
Tjoumakaris, Stavropoula
Clarençon, Frédéric
Limbucci, Nicola
Aziz-Sultan, Mohammad A
Cuellar-Saenz, Hugo H
Cognard, Christophe
Patel, Aman B
Dmytriw, Adam A
Student Authors
Faculty Advisor
Academic Program
UMass Chan Affiliations
Document Type
Publication Date
Subject Area
Collections
Embargo Expiration Date
Link to Full Text
Abstract
Objective: The Woven EndoBridge (WEB) device is an intrasaccular flow disruptor designed for wide-necked bifurcation aneurysms. These aneurysms may require the use of a concomitant stent. The objective of this study was to determine the clinical and radiological outcomes of patients undergoing stent-assisted WEB treatment. In addition, the authors also sought to determine the predictors of a concomitant stent in aneurysms treated with the WEB device.
Methods: The data for this study were taken from the WorldWideWEB Consortium, an international multicenter cohort including patients treated with the WEB device. Aneurysms were classified into two groups based on treatment: stent-assisted WEB and WEB device alone. The authors compared clinical and radiological outcomes of both groups. Univariable and multivariable binary logistic regression analyses were performed to determine factors that predispose to stent use.
Results: The study included 691 intracranial aneurysms (31 with stents and 660 without stents) treated with the WEB device. The adequate occlusion status did not differ between the two groups at the latest follow-up (83.3% vs 85.6%, p = 0.915). Patients who underwent stenting had more thromboembolic (32.3% vs 6.5%, p < 0.001) and procedural (16.1% vs 3.0%, p < 0.001) complications. Aneurysms treated with a concomitant stent had wider necks, greater heights, and lower dome-to-neck ratios. Increasing neck size was the only significant predictor for stent use.
Conclusions: This study demonstrates that there is no difference in the degree of aneurysm occlusion between the two groups; however, complications were more frequent in the stent group. In addition, a wider aneurysm neck predisposes to stent assistance in WEB-treated aneurysms.
Source
Diestro JDB, Dibas M, Adeeb N, Regenhardt RW, Vranic JE, Guenego A, Lay SV, Renieri L, Balushi AA, Shotar E, Premat K, Namaani KE, Saliou G, Möhlenbruch MA, Lylyk I, Foreman PM, Vachhani JA, Župančić V, Hafeez MU, Rutledge C, Rai H, Tutino VM, Mirshahi S, Ghozy S, Harker P, Alotaibi NM, Rabinov JD, Ren Y, Schirmer CM, Goren O, Piano M, Kühn AL, Michelozzi C, Elens S, Starke RM, Hassan AE, Salehani A, Nguyen A, Jones J, Psychogios M, Spears J, Marotta T, Pereira V, Parra-Fariñas C, Bres-Bullrich M, Mayich M, Salem MM, Burkhardt JK, Jankowitz BT, Domingo RA, Huynh T, Tawk R, Ulfert C, Lubicz B, Panni P, Puri AS, Pero G, Griessenauer CJ, Asadi H, Siddiqui A, Ducruet AF, Albuquerque FC, Patel N, Kan P, Kalousek V, Lylyk P, Boddu S, Stapleton CJ, Knopman J, Jabbour P, Tjoumakaris S, Clarençon F, Limbucci N, Aziz-Sultan MA, Cuellar-Saenz HH, Cognard C, Patel AB, Dmytriw AA. Stent-assisted Woven EndoBridge device for the treatment of intracranial aneurysms: an international multicenter study. J Neurosurg. 2023 Oct 20:1-9. doi: 10.3171/2023.8.JNS235. Epub ahead of print. PMID: 37862717.