A radical role for p38 MAPK in tumor initiation
Kennedy, Norman J. Cellurale, Cristina Arrigo Davis, Roger J.
Kennedy, Norman J.
Cellurale, Cristina Arrigo
Davis, Roger J.
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Student Authors
Cristina Cellurale
Faculty Advisor
Academic Program
MD/PhD
UMass Chan Affiliations
Document Type
Journal Article
Publication Date
2007-02-13
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Abstract
It is established that p38 MAPK can negatively regulate tumorigenesis, but the mechanism is incompletely understood. A new study in this issue of Cancer Cell shows that p38 MAP kinase plays a selective role in tumor initiation mediated by oxidative stress.
Source
Cancer Cell. 2007 Feb;11(2):101-3. Link to article on publisher's site
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DOI
10.1016/j.ccr.2007.01.009
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PubMed ID
17292820