Shedding light on sperm pHertility
Florman, Harvey M. Jungnickel, Melissa K. Sutton, Keith A.
Florman, Harvey M.
Jungnickel, Melissa K.
Sutton, Keith A.
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Faculty Advisor
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UMass Chan Affiliations
Document Type
Journal Article
Publication Date
2010-02-11
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Abstract
The acquisition of fertilization capacity by sperm is regulated by intracellular pH (pH(i)), but the transport pathways that regulate pH(i) are not well understood. Lishko et al. (2010) now report that Hv1, the voltage-sensitive proton channel, is present in human sperm and is an important regulator of the functional maturation of sperm.
Source
Cell. 2010 Feb 5;140(3):310-2. Link to article on publisher's site
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DOI
10.1016/j.cell.2010.01.035
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PubMed ID
20144756