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Autophagy SEPArates germline and somatic cells

Baehrecke, Eric H.
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Abstract

Cellular determinants of the germline selectively accumulate in germ cell precursors and influence cell fate during early development in many organisms. Zhang et al. (2009) now report that targeted autophagy mediated by the SEPA-1 protein depletes germplasm proteins from somatic cells during early development of the nematode.

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Cell. 2009 Jan 23;136(2):207-8. Link to article on publisher's site

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DOI
10.1016/j.cell.2009.01.003
PubMed ID
19167322
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