The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium
Dmytriw, Adam A ; Dibas, Mahmoud ; Ghozy, Sherief ; Adeeb, Nimer ; Diestro, Jose Danilo Bengzon ; Phan, Kevin ; Cuellar-Saenz, Hugo H ; Sweid, Ahmad ; Lay, Sovann V ; Guenego, Adrien ... show 10 more
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Authors
Dibas, Mahmoud
Ghozy, Sherief
Adeeb, Nimer
Diestro, Jose Danilo Bengzon
Phan, Kevin
Cuellar-Saenz, Hugo H
Sweid, Ahmad
Lay, Sovann V
Guenego, Adrien
Renieri, Leonardo
Al Balushi, Ali
Saliou, Guillaume
Möhlenbruch, Markus
Regenhardt, Robert W
Vranic, Justin E
Lylyk, Ivan
Foreman, Paul M
Vachhani, Jay A
Župančić, Vedran
Hafeez, Muhammad U
Rutledge, Caleb
Waqas, Muhammad
Tutino, Vincent M
Rabinov, James D
Ren, Yifan
Schirmer, Clemens M
Piano, Mariangela
Kühn, Anna L
Michelozzi, Caterina
Elens, Stéphanie
Starke, Robert M
Hassan, Ameer
Salehani, Arsalaan
Sporns, Peter
Jones, Jesse
Psychogios, Marios
Spears, Julian
Lubicz, Boris
Panni, Pietro
Puri, Ajit S
Pero, Guglielmo
Griessenauer, Christoph J
Asadi, Hamed
Stapleton, Christopher J
Siddiqui, Adnan
Ducruet, Andrew F
Albuquerque, Felipe C
Du, Rose
Kan, Peter
Kalousek, Vladimir
Lylyk, Pedro
Boddu, Srikanth
Tjoumakaris, Stavropoula
Knopman, Jared
Aziz-Sultan, Mohammad A
Limbucci, Nicola
Jabbour, Pascal
Cognard, Christophe
Patel, Aman B
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Abstract
Several studies have shown promising outcomes of the Woven EndoBridge (WEB) device for the treatment of wide-necked intracranial bifurcation aneurysms. This is a multicenter study attempts to explore the changes in trends and treatment outcomes over time for WEB embolization of intracranial aneurysms. The WorldWideWEB consortium is a retrospective multicenter collaboration of data from international centers spanning from January 2011 and June 2021, with no limitations on aneurysm location or rupture status. Both bifurcation and sidewall aneurysms were included. These patients were stratified based on treatment year into five treatment intervals: 2011-2015 (N = 66), 2016-2017 (N = 77), 2018 (N = 66), 2019 (N = 300), and 2020-2021 (N = 173). Patient characteristics and angiographic and clinical outcomes were compared between these time intervals. This study comprised 671 patients (median age 61.4 years; 71.2% female) with 682 intracranial aneurysms. Over time, we observed an increasing tendency to treat patients presenting with ruptured aneurysms and aneurysms with smaller neck, diameter, and dome widths. Furthermore, we observed a trend towards more off-label use of the WEB for sidewall aneurysms and increased adoption of transradial access for WEB deployment. Moreover, the proportion of patients with adequate WEB occlusion immediately and at last follow-up was significantly higher in more recent year cohorts, as well as lower rates of compaction and retreatment. Mortality and complications did not differ over time. This learning curve study suggests improved experience using the WEB for the treatment of intracranial aneurysms and has yielded higher rates of adequate occlusion over time.
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Dmytriw AA, Dibas M, Ghozy S, Adeeb N, Diestro JDB, Phan K, Cuellar-Saenz HH, Sweid A, Lay SV, Guenego A, Renieri L, Al Balushi A, Saliou G, Möhlenbruch M, Regenhardt RW, Vranic JE, Lylyk I, Foreman PM, Vachhani JA, Župančić V, Hafeez MU, Rutledge C, Waqas M, Tutino VM, Rabinov JD, Ren Y, Schirmer CM, Piano M, Kühn AL, Michelozzi C, Elens S, Starke RM, Hassan A, Salehani A, Sporns P, Jones J, Psychogios M, Spears J, Lubicz B, Panni P, Puri AS, Pero G, Griessenauer CJ, Asadi H, Stapleton CJ, Siddiqui A, Ducruet AF, Albuquerque FC, Du R, Kan P, Kalousek V, Lylyk P, Boddu S, Tjoumakaris S, Knopman J, Aziz-Sultan MA, Limbucci N, Jabbour P, Cognard C, Patel AB. The Woven EndoBridge (WEB) Device for the Treatment of Intracranial Aneurysms: Ten Years of Lessons Learned and Adjustments in Practice from the WorldWideWEB Consortium. Transl Stroke Res. 2022 Sep 6. doi: 10.1007/s12975-022-01072-x. Epub ahead of print. Erratum in: Transl Stroke Res. 2022 Sep 27;: PMID: 36066701.