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Elevated plasma interleukin-10 levels in acute dengue correlate with disease severity

Green, Sharone
Vaughn, D. W.
Kalayanarooj, Siripen
Nimmannitya, Suchitra
Suntayakorn, Saroj
Nisalak, Ananda
Rothman, Alan L.
Ennis, Francis A.
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Abstract

The goal of this study was to investigate further the role of Th1 cytokines, such as IL-12, and that of counterregulatory Th2 cytokines, such as IL-10, to fur- ther elucidate the possible immunological mechanisms responsible for the development of the plasma leakage seen in dengue hemorrhagic fever.

Source

J Med Virol. 1999 Nov;59(3):329-34. doi:10.1002/(SICI)1096-9071(199911)59:3<329::AID-JMV12>3.0.CO;2-G

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10.1002/(SICI)1096-9071(199911)59:3<329::AID-JMV12>3.0.CO;2-G
PubMed ID
10502265
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