Absence of hippocampal sclerosis in children with multiple daily seizures since infancy
Kothare, Sanjeev V. ; Sotrel, Ana ; Duchowny, Michael ; Jayakar, Prasanna ; Marshall, Paul C. ; Smith, Thomas W.
Kothare, Sanjeev V.
Sotrel, Ana
Duchowny, Michael
Jayakar, Prasanna
Marshall, Paul C.
Smith, Thomas W.
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UMass Chan Affiliations
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Journal Article
Publication Date
2001-08-01
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Abstract
We report a series of nine children with multiple daily seizures since infancy who underwent functional hemispherectomy that included en bloc resection of the hippocampus and the temporal neocortex. In all cases, the hippocampi were normal by conventional histology despite the fact that these patients had suffered from recurrent seizures over a long period of time. This observation suggests that extremely frequent seizures in childhood are not invariably associated with the development of hippocampal sclerosis.
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J Child Neurol. 2001 Aug;16(8):562-4. doi: 10.1177/088307380101600804
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DOI
10.1177/088307380101600804
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PubMed ID
11510925