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Integr-ating IL-1 alpha in antiviral host defenses

Fitzgerald, Katherine A
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Abstract

Adenoviral vectors used in gene therapy induce inflammation, although the underlying mechanisms are currently unknown. In this issue of Immunity, Di Paolo et al. (2009) implicate interleukin-1 alpha (IL- 1 alpha) in virus-induced inflammation and identify the beta 3 integrin as the key receptor regulating IL-1 alpha activity.

Source

Immunity. 2009 Jul 17;31(1):7-9. Link to article on publisher's site

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DOI
10.1016/j.immuni.2009.07.001
PubMed ID
19604487
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