Small RNA-Directed Silencing: The Fly Finds Its Inner Fission Yeast
Ge, Daniel Tianfang Zamore, Phillip D.
Ge, Daniel Tianfang
Zamore, Phillip D.
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UMass Chan Affiliations
Document Type
Journal Article
Publication Date
2013-04-22
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Abstract
Several recent studies demonstrate that piRNAs guide Piwi protein to repress transposon transcription in fly ovaries, much as fission yeast use siRNAs to silence repeat sequences. Still mysterious though is how Piwi targets euchromatic transposons for silencing, but not the specialized heterochromatic loci that produce piRNA precursors.
Source
Curr Biol. 2013 Apr 22;23(8):R318-20. doi: 10.1016/j.cub.2013.03.033. Link to article on publisher's site
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DOI
10.1016/j.cub.2013.03.033
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PubMed ID
23618667