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Comparison of outcomes research with clinical trials using preexisting data

Canto, John G.
Kiefe, Catarina I.
Williams, O. Dale
Barron, Hal V.
Rogers, William J.
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Abstract

Outcomes research using analysis of preexisting data is a relatively new field with the potential to improve the quality and effectiveness of medical care, and may provide a useful complement to randomized studies. Motivated by the growth of this research in the cardiovascular literature, this review offers a framework to identify the core concepts of outcomes research from database analyses by comparing and contrasting it with the randomized clinical trial.

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Am J Cardiol. 1999 Oct 15;84(8):923-7, A6.

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10532512
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