Comparison of outcomes research with clinical trials using preexisting data
Canto, John G. ; Kiefe, Catarina I. ; Williams, O. Dale ; Barron, Hal V. ; Rogers, William J.
Canto, John G.
Kiefe, Catarina I.
Williams, O. Dale
Barron, Hal V.
Rogers, William J.
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UMass Chan Affiliations
Document Type
Journal Article
Publication Date
1999-10-26
Keywords
Bias (Epidemiology)
*Cardiology
Causality
Cohort Studies
Confounding Factors (Epidemiology)
Data Collection
*Databases, Factual
Ethics, Medical
*Health Services Research
Humans
*Outcome Assessment (Health Care)
*Randomized Controlled Trials as Topic
Research Design
Bioinformatics
Biostatistics
Epidemiology
Health Services Research
*Cardiology
Causality
Cohort Studies
Confounding Factors (Epidemiology)
Data Collection
*Databases, Factual
Ethics, Medical
*Health Services Research
Humans
*Outcome Assessment (Health Care)
*Randomized Controlled Trials as Topic
Research Design
Bioinformatics
Biostatistics
Epidemiology
Health Services Research
Subject Area
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Abstract
Outcomes research using analysis of preexisting data is a relatively new field with the potential to improve the quality and effectiveness of medical care, and may provide a useful complement to randomized studies. Motivated by the growth of this research in the cardiovascular literature, this review offers a framework to identify the core concepts of outcomes research from database analyses by comparing and contrasting it with the randomized clinical trial.
Source
Am J Cardiol. 1999 Oct 15;84(8):923-7, A6.
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PubMed ID
10532512