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Comparison of efficacy, safety, and cost of low-molecular-weight heparin with continuous-infusion unfractionated heparin for initiation of anticoagulation after mechanical prosthetic valve implantation

Fanikos, John
Tsilimingras, Kanella
Kucher, Nils
Rosen, Allison B.
Hieblinger, Melissa D.
Goldhaber, Samuel Z.
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Abstract

We compared the efficacy, safety, and impact on postoperative hospital length of stay and inpatient hospital costs of low-molecular-weight heparin with that of unfractionated heparin as a "bridge" to achieving therapeutic levels of anticoagulation with warfarin in patients with newly implanted prosthetic heart valves. The patients who received low-molecular-weight heparin had a shorter length of stay and decreased postoperative costs compared with the control subjects receiving unfractionated heparin.

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Am J Cardiol. 2004 Jan 15;93(2):247-50.

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14715362
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