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Comparison of the duration of antimicrobial activity of 2 different antimicrobial central venous catheters

Matheos, Theofilos
Walz, J. Matthias
Adams, Janice P.
Johnson, Karen
Longtine, Karen J.
Longtine, Jaclyn K.
O'Neill, Melissa A.
Heard, Stephen O.
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Abstract

We compared the duration of antimicrobial effectiveness of 2 different antimicrobial catheters. The baseline activity of minocycline-rifampin catheters was greater than that of silver-platinum-carbon catheters against Staphylococcus aureus, Staphylococcus epidermidis, and Enterococcus faecalis. The antimicrobial activity of the minocycline-rifampin catheters against these pathogens persisted for up to 12 days, while that of the silver-platinum-carbon catheters was depleted by day 10 (P < .05).

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Infect Control Hosp Epidemiol. 2010 Mar;31(3):295-7. Link to article on publisher's site

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10.1086/650757
PubMed ID
20100086
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