Treatment of large intracranial aneurysms using the Woven EndoBridge (WEB): a propensity score-matched analysis
Musmar, Basel Salim, Hamza Adel Adeeb, Nimer Aslan, Assala Aljeradat, Bahaa Diestro, Jose Danilo Bengzon McLellan, Rachel M Algin, Oktay Ghozy, Sherief Dibas, Mahmoud
Citations
Authors
Salim, Hamza Adel
Adeeb, Nimer
Aslan, Assala
Aljeradat, Bahaa
Diestro, Jose Danilo Bengzon
McLellan, Rachel M
Algin, Oktay
Ghozy, Sherief
Dibas, Mahmoud
Lay, Sovann V
Guenego, Adrien
Renieri, Leonardo
Cancelliere, Nicole M
Carnevale, Joseph
Saliou, Guillaume
Mastorakos, Panagiotis
El Naamani, Kareem
Shotar, Eimad
Premat, Kevin
Möhlenbruch, Markus
Kral, Michael
Vranic, Justin E
Chung, Charlotte
Salem, Mohamed M
Lylyk, Ivan
Foreman, Paul M
Vachhani, Jay A
Shaikh, Hamza
Župančić, Vedran
Hafeez, Muhammad U
Catapano, Joshua
Waqas, Muhammad
Tutino, Vincent M
Ibrahim, Mohamed K
Mohammed, Marwa A
Ozates, M Ozgur
Ayberk, Giyas
Rabinov, James D
Ren, Yifan
Schirmer, Clemens M
Piano, Mariangela
Kühn, Anna L
Michelozzi, Caterina
Elens, Stéphanie
Starke, Robert M
Hassan, Ameer
Ogilvie, Mark
Nguyen, Anh
Jones, Jesse
Brinjikji, Waleed
Nawka, Marie T
Psychogios, Marios
Ulfert, Christian
Spears, Julian
Jankowitz, Brian T
Burkhardt, Jan-Karl
Domingo, Ricardo A
Huynh, Thien
Martinez-Gutierrez, Juan Carlos
Essibayi, Muhammed Amir
Sheth, Sunil A
Spiegel, Gary
Tawk, Rabih
Lubicz, Boris
Panni, Pietro
Puri, Ajit S
Pero, Guglielmo
Nossek, Erez
Raz, Eytan
Killer-Oberfalzer, Monika
Griessenauer, Christoph J
Asadi, Hamed
Siddiqui, Adnan
Brook, Allan
Altschul, David
Ducruet, Andrew F
Albuquerque, Felipe C
Regenhardt, Robert W
Stapleton, Christopher J
Kan, Peter
Kalousek, Vladimir
Lylyk, Pedro
Boddu, Srikanth
Knopman, Jared
Aziz-Sultan, Mohammad A
Tjoumakaris, Stavropoula I
Clarençon, Frédéric
Limbucci, Nicola
Cuellar-Saenz, Hugo H
Jabbour, Pascal M
Pereira, Vitor Mendes
Patel, Aman B
Dmytriw, Adam A
Student Authors
Faculty Advisor
Academic Program
UMass Chan Affiliations
Document Type
Publication Date
Keywords
Subject Area
Collections
Files
Embargo Expiration Date
Link to Full Text
Abstract
The Woven EndoBridge (WEB) device is primarily used for treating wide-neck intracranial bifurcation aneurysms under 10 mm. Limited data exists on its efficacy for large aneurysms. We aim to assess angiographic and clinical outcomes of the WEB device in treating large versus small aneurysms. We conducted a retrospective review of the WorldWide WEB Consortium database, from 2011 to 2022, across 30 academic institutions globally. Propensity score matching (PSM) was employed to compare small and large aneurysms on baseline characteristics. A total of 898 patients were included. There was no significant difference observed in clinical presentations, smoking status, pretreatment mRS, presence of multiple aneurysms, bifurcation location, or prior treatment between the two groups. After PSM, 302 matched pairs showed significantly lower last follow-up adequate occlusion rates (81% vs 90%, p = 0.006) and higher retreatment rates (12% vs 3.6%, p < 0.001) in the large aneurysm group. These findings may inform treatment decisions and patient counseling. Future studies are needed to further explore this area.
Source
Musmar B, Salim HA, Adeeb N, Aslan A, Aljeradat B, Diestro JDB, McLellan RM, Algin O, Ghozy S, Dibas M, Lay SV, Guenego A, Renieri L, Cancelliere NM, Carnevale J, Saliou G, Mastorakos P, El Naamani K, Shotar E, Premat K, Möhlenbruch M, Kral M, Vranic JE, Chung C, Salem MM, Lylyk I, Foreman PM, Vachhani JA, Shaikh H, Župančić V, Hafeez MU, Catapano J, Waqas M, Tutino VM, Ibrahim MK, Mohammed MA, Ozates MO, Ayberk G, Rabinov JD, Ren Y, Schirmer CM, Piano M, Kühn AL, Michelozzi C, Elens S, Starke RM, Hassan A, Ogilvie M, Nguyen A, Jones J, Brinjikji W, Nawka MT, Psychogios M, Ulfert C, Spears J, Jankowitz BT, Burkhardt JK, Domingo RA, Huynh T, Martinez-Gutierrez JC, Essibayi MA, Sheth SA, Spiegel G, Tawk R, Lubicz B, Panni P, Puri AS, Pero G, Nossek E, Raz E, Killer-Oberfalzer M, Griessenauer CJ, Asadi H, Siddiqui A, Brook A, Altschul D, Ducruet AF, Albuquerque FC, Regenhardt RW, Stapleton CJ, Kan P, Kalousek V, Lylyk P, Boddu S, Knopman J, Aziz-Sultan MA, Tjoumakaris SI, Clarençon F, Limbucci N, Cuellar-Saenz HH, Jabbour PM, Pereira VM, Patel AB, Dmytriw AA. Treatment of large intracranial aneurysms using the Woven EndoBridge (WEB): a propensity score-matched analysis. Neurosurg Rev. 2024 Jul 31;47(1):374. doi: 10.1007/s10143-024-02527-5. PMID: 39083214; PMCID: PMC11291542.