Clinically useful high-quality radiologic depiction relevant to radiologists' practice. Treatment-induced sarcoid-like reactions, due to T-cell mediated non-caseating granuloma formation, are increasingly encountered in the precision oncology era [1, 2]. Most commonly involved sites are the lungs and lymph nodes. Sarcoid-like reaction in bone marrow is rare, with fewer than 100 reported cases. On imaging, sarcoid-like reaction of bone marrow may mimic skeletal metastasis. Thus, it is important that radiologists be aware of this entity. Although imaging may suggest sarcoid-like reaction of bone marrow, definitive diagnosis requires biopsy.