In this issue of Menopause, the current study of the Women’s Health Initiative participants by Shadyab et al. adds a novel focus on extreme longevity, finding that survival to 90+ years was associated with later age at menarche, later age at natural or surgical menopause, and longer reproductive lifespan, with the last factor reflecting primarily age at menopause. Based on the multitude of studies, it is clear that reproductive factors are tied to more general measures of health.