The structure for a radiation oncology protocol. The Committee of Radiation Oncology Group Chairmen
Glicksman, Arvin S. ; Wasserman, Todd H. ; Bjarngard, Bengt ; Laurie, Fran
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Abstract
Multi-institutional Cooperative Group clinical trials involving radiotherapy require unambiguous therapeutic guidelines, so that patients entered from each of the participating institutions will receive essentially uniform treatment. The technical guidelines for a Radiation Oncology Protocol presented in this report represents a consensus of the Radiotherapy Committees in the major NCI funded Cooperative Groups and is derived from over a decade of experience. Although they have been written for external beam therapy, they are applicable to brachytherapy with appropriate technical considerations. It is anticipated that further evolution will occur with the introduction of new technologies such as 3-D treatment planning and delivery, multi-leaf collimation and small field irradiation.
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Int J Radiat Oncol Biol Phys. 1992;23(5):1079-82.