Hidradenitis suppurativa (HS) is an inflammatory skin condition predominantly affecting females in North America that has been found to be associated with anemia and leukocytosis. While thrombocytosis is not recognized as related to HS, it would be expected in a systemic inflammatory state. Laboratory abnormalities in severe HS patients can prompt unnecessary medical utilization due to concern for malignancy or infection, and we have observed patients undergo bone marrow biopsy unnecessarily. Better characterization of laboratory values can prevent unwarranted concern. We performed an Institutional Review Board-approved retrospective review of HS patients visiting an academic institution in Boston, MA, from 2015 to 2020.