To the Editor: We describe two patients with epidermolysis bullosa simplex, Dowling-Meara type (EBS-DM), who also have loose anagen hair syndrome (LAHS). EBS-DM is a severe form of EBS marked by widespread herpetiform blistering, worse during infancy.¹ LAHS is diagnosed by the ability to painlessly extract anagen hairs from the scalp that lack an external root sheath and demonstrate cuticle ruffling distal to a misshapen bulb.² The hair is typically sparse and seldom requires cutting.² An association between these entities has not previously been reported, to our knowledge.