Evaluation of extended and continuous use oral contraceptives
Wright, Kristen Page ; Johnson, Julia V.
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Abstract
Oral contraceptives are classically given in a cyclic manner with 21 days of active pills followed by 7 days of placebo. In the past 4 years, new oral contraceptives have been introduced which either shorten the placebo time, lengthen the active pills (extended cycle), or provide active pills every day (continuous). These concepts are not new; extended and continuous pills were first studied in the 1960s and 1970s and have been provided in an off-label manner by gynecologists to treat menstrual disorders, such as menorrhagia and dysmenorrhea, and gynecologic disorders, such as endometriosis. Now that extended and continuous combined oral contraceptives are available for all patients, it is critical for providers to understand the physiology, dosing, side effects, and benefits of this form of oral contraceptive. This article reviews the history and the potential uses of the new continuous combined oral contraceptive.
Source
Wright KP, Johnson JV. Evaluation of extended and continuous use oral contraceptives. Ther Clin Risk Manag. 2008 Oct;4(5):905-11. doi: 10.2147/tcrm.s2143. PMID: 19209272; PMCID: PMC2621397. Link to article on publisher's website
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Notes
At the time of publication, Julia Johnson was not yet affiliated with the University of Massachusetts Medical School.