Selective expression of histone genes in mouse-human hybrid cells
Marashi, Farhad Croce, Carlo M. Stein, Janet L. Stein, Gary S.
Marashi, Farhad
Croce, Carlo M.
Stein, Janet L.
Stein, Gary S.
Citations
Altmetric:
Student Authors
Faculty Advisor
Academic Program
UMass Chan Affiliations
Document Type
Journal Article
Publication Date
1985-08-01
Subject Area
Embargo Expiration Date
Link to Full Text
Abstract
Mouse-human hybrid cells preferentially segregating mouse chromosomes contain predominantly human histone mRNAs and synthesize human histone proteins. In contrast, hybrids segregating human chromosomes contain both human and murine histone mRNAs, yet synthesize only mouse histone proteins. These results suggest transcriptional control of histone gene expression in hybrids segregating mouse chromosomes and post-transcriptional regulation in hybrids segregating human chromosomes.
Source
Exp Cell Res. 1985 Aug;159(2):280-6.
Year of Medical School at Time of Visit
Sponsors
Dates of Travel
DOI
Permanent Link to this Item
PubMed ID
4029271