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Reduced-representation methylation mapping

Jeddeloh, Jeffrey A.
Greally, John M.
Rando, Oliver J.
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Abstract

The power of massively parallel sequencing has been harnessed to map cytosine methylation patterns in the mouse genome, allowing insights into the relationship of methylation with DNA sequence, histone modifications, transcriptional activity and dynamic changes in methylation status during differentiation.

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Genome Biol. 2008;9(8):231. Epub 2008 Sep 1. Link to article on publisher's site

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DOI
10.1186/gb-2008-9-8-231
PubMed ID
18771577
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