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Acute kidney injury due to intravenous bleach injection

Ashish, Verma
Vanguri, Vijay
Golla, Venkata
Rhyee, Sean Hyun
Trainor, Matthew
Konstantin, Abramov
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Abstract

INTRODUCTION: Sodium hypochlorite is the active ingredient in bleach, a ubiquitous household disinfectant, and has known toxicities depending on route of exposure and amount. Acute kidney injury due to sodium hypochlorite exposure has never been reported. Patients that did develop nephrotoxicity following bleach exposure did so due to development of other risk factors for kidney injury such as volume depletion or sepsis.

DISCUSSION: We report a patient who presented with black urine after parenteral self-administration of a large quantity of bleach. We review the clinical presentation, laboratory and biopsy findings, and outcome as well as discuss possible mechanisms of sodium hypochlorite toxicity and management strategies.

Source

J Med Toxicol. 2013 Mar;9(1):71-4. doi: 10.1007/s13181-012-0259-6. Link to article on publisher's site

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10.1007/s13181-012-0259-6
PubMed ID
22961673
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