The clinical utilities of multi-pinhole single photon emission computed tomography
Ozsahin, Ilker Chen, Ling Konik, Arda King, Michael A Beekman, Freek J. Mok, Greta S. P.
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Abstract
Single photon emission computed tomography (SPECT) is an important imaging modality for various applications in nuclear medicine. The use of multi-pinhole (MPH) collimators can provide superior resolution-sensitivity trade-off when imaging small field-of-view compared to conventional parallel-hole and fan-beam collimators. Besides the very successful application in small animal imaging, there has been a resurgence of the use of MPH collimators for clinical cardiac and brain studies, as well as other small field-of-view applications. This article reviews the basic principles of MPH collimators and introduces currently available and proposed clinical MPH SPECT systems.
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Ozsahin I, Chen L, Könik A, King MA, Beekman FJ, Mok GSP. The clinical utilities of multi-pinhole single photon emission computed tomography. Quant Imaging Med Surg. 2020 Oct;10(10):2006-2029. doi: 10.21037/qims-19-1036. PMID: 33014732; PMCID: PMC7495312. Link to article on publisher's site