Gaining Insight into Vitiligo Genetics through the Lens of a Large Epidemiologic Study
Okamura, Ken Garber, Manuel Harris, John E.
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Abstract
Several epidemiologic studies and GWASs have implicated genetic factors in the pathogenesis of vitiligo. The report by Kim et al. (2020) describes a prospective cohort study from Korea that has the greatest statistical power to date in addressing the epidemiology of vitiligo inheritance. The authors reported the incidence risk ratios in individuals whose first-degree relatives or spouses are affected, providing clear evidence that both genetic and nongenetic factors influence the pathogenesis of vitiligo.
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Okamura K, Garber M, Harris JE. Gaining Insight into Vitiligo Genetics through the Lens of a Large Epidemiologic Study. J Invest Dermatol. 2021 Apr;141(4):718-721. doi: 10.1016/j.jid.2020.10.005. PMID: 33752810. Link to article on publisher's site