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Introduction. Formation, growth, and rupture: the biology and physics of cerebral aneurysms

Prestigiacomo, Charles J.
Gounis, Matthew J
Gonzalez, L. Fernando
Frosen, Juhana
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Authors
Prestigiacomo, Charles J.
Gounis, Matthew J
Gonzalez, L. Fernando
Frosen, Juhana
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Faculty Advisor
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UMass Chan Affiliations
Document Type
Journal Article
Publication Date
2019-07-01
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Abstract

his issue of Neurosurgical Focus addresses several of the important biological and genetic aspects of aneurysm formation. The reader will be exposed to the latest theories of aneurysm formation that invoke genetic predispositions and the role of inflammation and matrix metalloproteinases in the genesis of a cerebral aneurysm. Observational studies provide additional insight into the role of estrogen and other female sex steroids and tobacco use with respect to the evolution of multiple aneurysms.

Source

Neurosurg Focus. 2019 Jul 1;47(1):E1. doi: 10.3171/2019.4.FOCUS19333. Link to article on publisher's site

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DOI
10.3171/2019.4.FOCUS19333
PubMed ID
31261113
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