An autophagy-independent function for Beclin 1 in cancer
Rohatgi, Rasika ; Shaw, Leslie M.
Rohatgi, Rasika
Shaw, Leslie M.
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UMass Chan Affiliations
Document Type
Journal Article
Publication Date
2016-01-02
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Abstract
The involvement of Beclin 1 in cancer has been attributed primarily to its role in autophagy initiation. Our recent findings identify a novel, alternative mechanism by which Beclin 1 can impact tumor progression, through the regulation of growth factor receptor signaling.
Source
Mol Cell Oncol. 2016 Jan 2;3(1). pii: e1030539. Epub 2015 Apr 14. Link to article on publisher's site
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DOI
10.1080/23723556.2015.1030539
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PubMed ID
26998512