Loading...
Thumbnail Image
Publication

SARS-CoV-2 Vaccination and Solid Organ Transplant Patients: Data Needed to Inform Safety and Efficacy

Ison, Michael G.
Avery, Robin
Blumberg, Emily
Chin-Hong, Peter
Halasa, Natasha
Kaul, Dan
Pergam, Steve
Theodoropoulos, Nicole M.
Wolfe, Cameron R.
Embargo Expiration Date
Abstract

Solid organ transplant (SOT) recipients appear to have higher rates of mortality from COVID-19 when compared to other populations, attributed to underlying immunosuppression and concomitant co-morbidities.1 Such findings are consistent with other respiratory viral infections that are associated with an increased risk of morbidity and mortality in immunocompromised hosts.2 Further, these patients experience prolonged SARS-CoV-2 shedding which has been linked to emergence of viral mutants. Prolonged shedding also poses a risk of transmission and requires prolonged isolation, potentially leading to delays in medical care.

Source

Ison MG, Avery R, Blumberg E, Chin-Hong P, Halasa N, Kaul D, Pergam S, Theodoropoulos NM, Wolfe CR. SARS-CoV-2 Vaccination and Solid Organ Transplant Patients: Data Needed to Inform Safety and Efficacy. Transplantation. 2021 Mar 10. doi: 10.1097/TP.0000000000003747. Epub ahead of print. PMID: 33724250. Link to article on publisher's site

Year of Medical School at Time of Visit
Sponsors
Dates of Travel
DOI
10.1097/TP.0000000000003747
PubMed ID
33724250
Other Identifiers
Notes
Funding and Acknowledgements
Corresponding Author
Related Resources
Related Resources
Repository Citation
Rights
Distribution License