Assessment of liver fat in an obese patient population using noncontrast CT fat percent index
Jon, Ali F. Cheema, Ahmad R. Khan, Atif N. Raptopoulos, Vassilios Hauser, Thomas Nasser, Imad Welty, Francine K. Karellas, Andrew Clouse, Melvin E.
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Abstract
OBJECTIVE: To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S).
METHODS: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI = [(65-patient HU)/65]x100, normal live r = 65 HU.
RESULTS: There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r = -0.901), CTL-S (r = -0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P < .05).
CONCLUSION: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.
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Clin Imaging. 2014 May-Jun;38(3):259-64. doi: 10.1016/j.clinimag.2014.01.005. Epub 2014 Jan 17. Link to article on publisher's site