Life after acute fibrinous and organizing pneumonia: a case report of a patient 30 months after diagnosis and review of the literature
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UMass Chan Affiliations
Department of Medicine, Division of Pulmonary, Allergy and Critical Care MedicineDepartment of Anesthesiology
Document Type
Journal ArticlePublication Date
2016-02-01
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Acute fibrinous and organizing pneumonia (AFOP) is a rare histologic interstitial pneumonia pattern recently described in the literature with fewer than 120 cases published. AFOP is often difficult to diagnose and may be mistaken for other pulmonary disorders such as interstitial pneumonias or pneumonitides. Patients often present with vague symptoms of cough, dyspnea, hemoptysis, fatigue, and occasionally respiratory failure. Radiological findings show diffuse patchy opacities and ground glass appearance of the lungs. On histologic examination, intra-alveolar fibrin balls are observed. We discuss a case of a man who presented with hemoptysis and dyspnea and whose open lung biopsy revealed AFOP. We will describe the presentation, diagnosis, and post-discharge course, and review the current literature. There are only 4 cases which have reported the patients' course of disease after 1 year, the longest being 2 years. To our knowledge, this is the only case of AFOP in the literature that describes the course of a patient more than 2 years after the diagnosis of AFOP, and is the most comprehensive review of the current literature.Source
J Crit Care. 2016 Feb;31(1):255-61. doi: 10.1016/j.jcrc.2015.10.002. Epub 2015 Oct 9. Link to article on publisher's siteDOI
10.1016/j.jcrc.2015.10.002Permanent Link to this Item
http://hdl.handle.net/20.500.14038/25753PubMed ID
26578116Related Resources
Link to Article in PubMedae974a485f413a2113503eed53cd6c53
10.1016/j.jcrc.2015.10.002