Identifying Regions Enriched in a ChIP-seq Data Set (Peak Finding)

Authors
Hung, Jui-Hung
Weng, Zhiping
UMass Chan Affiliations
Department of Biochemistry and Molecular Pharmacology
Program in Bioinformatics and Integrative Biology
Document Type
Journal Article
Publication Date
2017-02-01
Keywords
Bioinformatics
Computational Biology

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Link to Full Text
http://dx.doi.org/10.1101/pdb.prot093187
Abstract
This protocol demonstrates how to use MACS software to call peaks in a ChIP-seq data set. MACS is one of the most widely used peak-calling programs. The protocol describes how to run MACS in a UNIX environment and on Galaxy and how to extract the sequences of +/-50 bp around the summits of the 500 MACS peaks with the most significant P values.
Source
Cold Spring Harb Protoc. 2017 Feb 1;2017(2):pdb.prot093187. doi: 10.1101/pdb.prot093187. Link to article on publisher's site
DOI
10.1101/pdb.prot093187
Permanent Link to this Item
http://hdl.handle.net/20.500.14038/25814
PubMed ID
27574193
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