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dc.contributor.authorPierce, Brian G.
dc.contributor.authorWiehe, Kevin
dc.contributor.authorHwang, Howook
dc.contributor.authorKim, Bong-Hyun
dc.contributor.authorVreven, Thom
dc.contributor.authorWeng, Zhiping
dc.date2022-08-11T08:07:59.000
dc.date.accessioned2022-08-23T15:38:20Z
dc.date.available2022-08-23T15:38:20Z
dc.date.issued2014-06-15
dc.date.submitted2015-06-24
dc.identifier.citationBioinformatics. 2014 Jun 15;30(12):1771-3. doi: 10.1093/bioinformatics/btu097. Epub 2014 Feb 14. <a href="http://dx.doi.org/10.1093/bioinformatics/btu097">Link to article on publisher's site</a>
dc.identifier.issn1367-4803 (Linking)
dc.identifier.doi10.1093/bioinformatics/btu097
dc.identifier.pmid24532726
dc.identifier.urihttp://hdl.handle.net/20.500.14038/25916
dc.description.abstractSUMMARY: Protein-protein interactions are essential to cellular and immune function, and in many cases, because of the absence of an experimentally determined structure of the complex, these interactions must be modeled to obtain an understanding of their molecular basis. We present a user-friendly protein docking server, based on the rigid-body docking programs ZDOCK and M-ZDOCK, to predict structures of protein-protein complexes and symmetric multimers. With a goal of providing an accessible and intuitive interface, we provide options for users to guide the scoring and the selection of output models, in addition to dynamic visualization of input structures and output docking models. This server enables the research community to easily and quickly produce structural models of protein-protein complexes and symmetric multimers for their own analysis. AVAILABILITY: The ZDOCK server is freely available to all academic and non-profit users at: http://zdock.umassmed.edu. No registration is required.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=24532726&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://www.ncbi.nlm.nih.gov/pmc/articles/PMC4058926/
dc.subjectAlgorithms
dc.subjectMolecular Docking Simulation
dc.subjectMultiprotein Complexes
dc.subjectProtein Multimerization
dc.subject*Software
dc.subjectBiochemistry, Biophysics, and Structural Biology
dc.subjectBioinformatics
dc.subjectComputational Biology
dc.subjectIntegrative Biology
dc.subjectSystems Biology
dc.titleZDOCK server: interactive docking prediction of protein-protein complexes and symmetric multimers
dc.typeArticle
dc.source.journaltitleBioinformatics (Oxford, England)
dc.source.volume30
dc.source.issue12
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/bioinformatics_pubs/57
dc.identifier.contextkey7256016
html.description.abstract<p>SUMMARY: Protein-protein interactions are essential to cellular and immune function, and in many cases, because of the absence of an experimentally determined structure of the complex, these interactions must be modeled to obtain an understanding of their molecular basis. We present a user-friendly protein docking server, based on the rigid-body docking programs ZDOCK and M-ZDOCK, to predict structures of protein-protein complexes and symmetric multimers. With a goal of providing an accessible and intuitive interface, we provide options for users to guide the scoring and the selection of output models, in addition to dynamic visualization of input structures and output docking models. This server enables the research community to easily and quickly produce structural models of protein-protein complexes and symmetric multimers for their own analysis.</p> <p>AVAILABILITY: The ZDOCK server is freely available to all academic and non-profit users at: http://zdock.umassmed.edu. No registration is required.</p>
dc.identifier.submissionpathbioinformatics_pubs/57
dc.contributor.departmentProgram in Bioinformatics and Integrative Biology
dc.source.pages1771-3


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