Correlation of DNA adenine methylase activity with spontaneous mutability in Escherichia coli K-12

Authors
Marinus, Martin G.
Poteete, Anthony R.
Arraj, Judy A.
UMass Chan Affiliations
Department of Biochemistry and Molecular Pharmacology
Document Type
Journal Article
Publication Date
1984-04-01
Keywords
Bacterial Proteins
DNA Repair
DNA, Bacterial
Escherichia coli
Methyltransferases
*Mutation
Plasmids
Site-Specific DNA-Methyltransferase (Adenine-Specific)
Biochemistry, Biophysics, and Structural Biology

Metadata
Show full item record
Link to Full Text
http://dx.doi.org/10.1016/0378-1119(84)90095-7
Abstract
Using a multicopy plasmid in which the tac promoter has been placed in front of the dam gene of Escherichia coli K-12, we show that levels of DNA adenine methylase activity are correlated with the spontaneous mutation frequency.
Source
Gene. 1984 Apr;28(1):123-5.
Permanent Link to this Item
http://hdl.handle.net/20.500.14038/26061
PubMed ID
6376282
Related Resources
Link to Article in PubMed
Collections