Growth-rate-dependent transcription initiation from the dam P2 promoter
Name:
Publisher version
UMass Chan Affiliations
Department of Biochemistry and Molecular PharmacologyDocument Type
ArticlePublication Date
1995-05-19Keywords
Base SequenceColon
Escherichia coli
Escherichia coli Proteins
*Gene Expression Regulation, Bacterial
Humans
Methyltransferases
*Promoter Regions, Genetic
Recombinant Fusion Proteins
*Site-Specific DNA-Methyltransferase (Adenine-Specific)Substrate Specificitybeta-GalactosidaseDNA methylationlipoic acid ligaserecombinant DNAgene regulationBacteriaBiochemistry, Biophysics, and Structural BiologyGenetic PhenomenaPharmacology, Toxicology and Environmental Health
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Show full item recordAbstract
Transcription of the dam gene in Escherichia coli is dependent on growth rate. Using single-copy promoter::lacZYA fusions we found that of the five promoter regions which affect dam expression, only the P2 promoter shows growth-rate dependence. The determinants for growth-rate control must lie in the region -52 to +27 relative to the transcription start point.Source
Gene. 1995 May 19;157(1-2):213-5.