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dc.contributor.authorHorst, Jens-Peter
dc.contributor.authorWu, Te-hui
dc.contributor.authorMarinus, Martin G.
dc.date2022-08-11T08:08:00.000
dc.date.accessioned2022-08-23T15:39:11Z
dc.date.available2022-08-23T15:39:11Z
dc.date.issued1999-03-09
dc.date.submitted2009-01-12
dc.identifier.citationTrends Microbiol. 1999 Jan;7(1):29-36.
dc.identifier.issn0966-842X (Print)
dc.identifier.pmid10068995
dc.identifier.urihttp://hdl.handle.net/20.500.14038/26108
dc.description.abstractThe isolation and characterization of Escherichia coli mutator genes have led to a better understanding of DNA replication fidelity mechanisms and to the discovery of important DNA repair pathways and their relationship to spontaneous mutagenesis. Mutator strains in a population of cells can be beneficial in that they allow rapid selection of variants during periods of stress, such as drug exposure.
dc.language.isoen_US
dc.relation<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&list_uids=10068995&dopt=Abstract">Link to Article in PubMed</a>
dc.relation.urlhttp://dx.doi.org/10.1016/S0966-842X(98)01424-3
dc.subjectDNA Repair
dc.subjectEscherichia coli
dc.subjectEscherichia coli Infections
dc.subject*Genes, Bacterial
dc.subjectHumans
dc.subject*Mutagenesis
dc.subjectBiochemistry, Biophysics, and Structural Biology
dc.subjectPharmacology, Toxicology and Environmental Health
dc.titleEscherichia coli mutator genes
dc.typeJournal Article
dc.source.journaltitleTrends in microbiology
dc.source.volume7
dc.source.issue1
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/bmp_pp/47
dc.identifier.contextkey692463
html.description.abstract<p>The isolation and characterization of Escherichia coli mutator genes have led to a better understanding of DNA replication fidelity mechanisms and to the discovery of important DNA repair pathways and their relationship to spontaneous mutagenesis. Mutator strains in a population of cells can be beneficial in that they allow rapid selection of variants during periods of stress, such as drug exposure.</p>
dc.identifier.submissionpathbmp_pp/47
dc.contributor.departmentDepartment of Biochemistry and Molecular Pharmacology
dc.source.pages29-36


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