Enhancing integrin function by VEGF/neuropilin signaling: Implications for tumor biology
UMass Chan AffiliationsDepartment of Cancer Biology
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AbstractThis review advances the hypothesis that the ability of integrins to engage their extracellular matrix ligands and signal can be regulated in tumor cells by vascular endothelial growth factor (VEGF), a major angiogenic factor that also has direct effects on the function of tumor cells. More specifically, we will discuss how neuropilins (NRPs), a distinct class of VEGF receptors, enable the function of specific integrins that contribute to tumor initiation and progression.
Cell Adh Migr. 2012 Oct 17;6(6). Link to article on publisher's site
Permanent Link to this Itemhttp://hdl.handle.net/20.500.14038/26292
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