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dc.contributor.authorMatthews, Charles E.
dc.contributor.authorOckene, Ira S.
dc.contributor.authorFreedson, Patty S.
dc.contributor.authorRosal, Milagros C.
dc.contributor.authorMerriam, Philip A.
dc.contributor.authorHebert, James R.
dc.date2022-08-11T08:08:02.000
dc.date.accessioned2022-08-23T15:40:05Z
dc.date.available2022-08-23T15:40:05Z
dc.date.issued2002-08-08
dc.date.submitted2008-03-11
dc.identifier.citation<p>Med Sci Sports Exerc. 2002 Aug;34(8):1242-8.</p>
dc.identifier.issn0195-9131 (Print)
dc.identifier.pmid12165677
dc.identifier.urihttp://hdl.handle.net/20.500.14038/26322
dc.description.abstractPURPOSE: A "J"-shaped model has been proposed to describe the relationship between physical activity and risk of upper-respiratory tract infection (URTI). However, little epidemiologic evidence is available to support the contention that moderately active individuals are at lowest risk of URTI. This investigation examined differences in URTI risk between physically inactive and moderately active adults. METHODS: Observational study of 547 healthy adults (49% women) aged 20-70 yr reported URTI events at 90-d intervals over 12-month of follow-up (5 evaluations). Three 24-h physical activity recalls per evaluation were obtained and averaged to quantify total moderate-vigorous activity (> or =3.0 metabolic equivalents [MET]). Associations between URTI and physical activity levels were estimated using incidence rate ratios (IRR) derived using Poisson regression while adjusting for a number of potential confounders including age, education, anxiety, cynicism, and selected dietary factors. RESULTS: Men and women reported 1.2 (1.4) and 1.2 (1.2) URTI events per year, respectively (mean [(SD]). Adjusting for gender and potential confounders, the IRR for less than 3.93, 3.94-7.15, 7.16-11.95, and > or = 11.96 MET-h.d(-1) among men, and less than 2.38, 2.39-4.09, 4.10-6.24, and > or = 6.25 MET-h.d(-1) among women, were 1.00 (referent), 0.87 (95% confidence interval [CI], 0.70-1.07), 0.88 (95% CI, 0.71-1.09), and 0.77 (95% CI, 0.62-0.95), respectively (P(trend) = 0.03). This effect was stronger in men (P(trend) = 0.03) than women (P(trend) = 0.17), although at similar expenditure levels (6-7 MET-h.d-1), risk was reduced by about 20% in men and women. Risk reduction was most pronounced in the fall of the year (P(trend) = 0.02). CONCLUSIONS: These data support the hypothesis that moderate levels of physical activity are associated with a reduced risk for URTI.
dc.language.isoen_US
dc.relation<p><a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12165677&dopt=Abstract ">Link to article in PubMed</a></p>
dc.relation.urlhttps://doi.org/10.1097/00005768-200208000-00003
dc.subjectAdult
dc.subjectAge Distribution
dc.subjectAged
dc.subjectCohort Studies
dc.subjectConfidence Intervals
dc.subjectExercise
dc.subjectExertion
dc.subjectFemale
dc.subjectHumans
dc.subjectIncidence
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectPhysical Fitness
dc.subjectPoisson Distribution
dc.subjectProbability
dc.subjectProspective Studies
dc.subjectReference Values
dc.subjectRespiratory Tract Infections
dc.subjectRisk Factors
dc.subjectSex Distribution
dc.subjectCardiology
dc.subjectCardiovascular Diseases
dc.titleModerate to vigorous physical activity and risk of upper-respiratory tract infection
dc.typeJournal Article
dc.source.journaltitleMedicine and science in sports and exercise
dc.source.volume34
dc.source.issue8
dc.identifier.legacycoverpagehttps://escholarship.umassmed.edu/cardio_pp/10
dc.identifier.contextkey456895
html.description.abstract<p>PURPOSE: A "J"-shaped model has been proposed to describe the relationship between physical activity and risk of upper-respiratory tract infection (URTI). However, little epidemiologic evidence is available to support the contention that moderately active individuals are at lowest risk of URTI. This investigation examined differences in URTI risk between physically inactive and moderately active adults.</p> <p>METHODS: Observational study of 547 healthy adults (49% women) aged 20-70 yr reported URTI events at 90-d intervals over 12-month of follow-up (5 evaluations). Three 24-h physical activity recalls per evaluation were obtained and averaged to quantify total moderate-vigorous activity (> or =3.0 metabolic equivalents [MET]). Associations between URTI and physical activity levels were estimated using incidence rate ratios (IRR) derived using Poisson regression while adjusting for a number of potential confounders including age, education, anxiety, cynicism, and selected dietary factors.</p> <p>RESULTS: Men and women reported 1.2 (1.4) and 1.2 (1.2) URTI events per year, respectively (mean [(SD]). Adjusting for gender and potential confounders, the IRR for less than 3.93, 3.94-7.15, 7.16-11.95, and > or = 11.96 MET-h.d(-1) among men, and less than 2.38, 2.39-4.09, 4.10-6.24, and > or = 6.25 MET-h.d(-1) among women, were 1.00 (referent), 0.87 (95% confidence interval [CI], 0.70-1.07), 0.88 (95% CI, 0.71-1.09), and 0.77 (95% CI, 0.62-0.95), respectively (P(trend) = 0.03). This effect was stronger in men (P(trend) = 0.03) than women (P(trend) = 0.17), although at similar expenditure levels (6-7 MET-h.d-1), risk was reduced by about 20% in men and women. Risk reduction was most pronounced in the fall of the year (P(trend) = 0.02).</p> <p>CONCLUSIONS: These data support the hypothesis that moderate levels of physical activity are associated with a reduced risk for URTI.</p>
dc.identifier.submissionpathcardio_pp/10
dc.contributor.departmentDepartment of Medicine, Division of Preventive and Behavioral Medicine
dc.contributor.departmentDepartment of Medicine, Division of Cardiovascular Medicine
dc.source.pages1242-8


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